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She will substitute for her colleague during the meeting.
The substitute teacher took over the class seamlessly.

"}},{"@type":"Question","name":"What are the synonyms of \"substitute\"?","acceptedAnswer":{"@type":"Answer","text":"

backup: support, reserve, duplicate
exchange: trade, swap, interchange, barter
proxy: representative, substitute, deputy, agent
replace: substitute, exchange, fill in, supplant
swap: exchange, trade, switch

"}},{"@type":"Question","name":"What are the antonyms of \"substitute\"?","acceptedAnswer":{"@type":"Answer","text":"

main: chief, principal, primary, central
original: initial, first, authentic
primary: main, chief, initial, fundamental
retain: to keep possession of, to remember

"}}]}