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His reaction to the news was one of shock.
The chemical reaction produced a violent explosion.

"}},{"@type":"Question","name":"What are the synonyms of \"reaction\"?","acceptedAnswer":{"@type":"Answer","text":"

feedback: response, opinion, reaction, input
reflex: an automatic response to a stimulus, an action that is performed without conscious thought
reply: response, answer, retort, counter
response: reply, answer, reaction, feedback
retaliation: revenge, payback, reprisal, vengeance

"}},{"@type":"Question","name":"What are the antonyms of \"reaction\"?","acceptedAnswer":{"@type":"Answer","text":"

inaction: absence of action, inactivity, failure to act
unresponsiveness: lack of reaction or response

"}}]}